1. Conduct biological target-related information analysis.

2. Conduct homologous modelling and QSAR modelling of biological target points and realize scaffold hopping.

3. Conduct virtual screening and discover new hits.

4. Based on drug molecular design of target structures, cooperate with other drug research and development teams to formulate and optimize strategies for drug research and development. 

5. Follow the latest news of computer-aided drug design and introduce new technologies and methods.

1. Hold a Master’s Degree or above and majored in those related to computational chemistry, pharmaceutical chemistry, organic chemistry, etc.

2. Have no less than three years of experience in computer-aided drug design of the new drug research and development field and need to have experience in design of nucleic acid drug carriers and polypeptides.

3. Be familiar with the elementary knowledge of pharmaceutical chemistry, be good at analyzing the relationship between compound structures and their activity and druggability and be familiar with homologous modelling and QSAR modelling.

4. Be skilled at adapting biological targets to macromolecular and micromolecular drugs, explain the adaption results reasonably and give instructive suggestions on further structural optimization and design.

5. carry out virtual screening work and help discover new hits.

6. Be skilled at reading the English literature. 

7. Have a team spirit and communicate and cooperate with other departments well.